Fig. 3

Immunohistochemical profiles of papillary renal neoplasm with reverse polarity (PRNRP). a GATA3 showing strong nuclear positivity (IHC × 200). b MUC1 was strongly positive on apical membrane, exhibiting polar reversal (IHC × 200). c 34bE12 showing membrane positivity (IHC × 200). d Basolateral-membranous ‘cup-like’ staining of E-cadherin (IHC × 200). e Basolateral-membranous ‘cup-like’ staining of Ksp-cadherin (IHC × 200). f Vimentin was negative in tumor cells but positive in the fibrovascular axis (IHC × 200)