Fig. 2
From: High incidence of HPV infection in minors with oral squamous cell carcinoma

Representative images of histological characteristics, immunohistochemical staining and FISH. A and D Excised tissue stained with hematoxylin and eosin showing the histologic appearance of well-differentiated and middle differentiated squamous cell carcinoma. B and E Positive immunostaining for p16 in OSCC. C and F Examples of HPV mRNA detection with FISH showing yielded positive results in OSCC. (C’ and F’ are higher-magnification views of boxed areas) Scar Bar: 500 μm (A, B, D and E) 0.100 μm (C, F), 25 μm (C’, F’)