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Table 2 Summary of the main characteristics of TFEB translocation renal cell carcinoma and TFEB amplification renal cell carcinoma

From: A rare case of TFEB/6p21/VEGFA-amplified renal cell carcinoma diagnosed by whole-exome sequencing: clinicopathological and genetic feature report and literature review

Cases

Age  (Mean,  year)

Sex  (Male:  female)

Size  (Mean,  cm)

 ≥ pT3

Metastasis (follow-up)

Papillary

Tubulopapillary

Pseudopapillary

Morphologic features

Necrosis

Calcification

Pigment

TFEB

IHC(Positivity)

HMB45

Eosinophilic

Clear Cell

cathepsin k

Melan-A

TFEB-

 Amplified Tumors TFEB

50

63.46

3:2

8.73

30/50

15/20

14/45

18/45

6/45

27/45

20/45

7/45

/

/

5/7

16/27

28/36

6/30

 Translocated Tumors

40

45.6

2:3

7.09

8/24

1/8

5/25

4/25

3/25

7/25

16/25

3/25

3/25

3/25

12/12

36/36

34/35

21/30

p

0.000

/

0.088

0.047

0.004

0.406

0.059

1.000

0.013

0.140

1.000

/

/

0.123

0.000

0.028

0.000

  1. Statistical analysis was performed by Fisher’s exact test
  2. Abbreviations: IHC Immunohistochemistry