Fig. 1
From: Evaluation of the rapid Idylla IDH1-2 mutation assay in FFPE glioma samples
The H&E and IDH1 R132H IHC sections are shown for case 20. Morphology and other immunohistochemical findings raised the clinical suspicion of an IDH1/2 alteration (A). However, IHC for IDH1 R132H was negative, demonstrating only a background non-specific blush interpreted as negative (B). The positive control is shown in the inset for reference. NGS and Idylla testing revealed IDH1 p.R132C alteration