Table 2 Differential diagnosis of CIC::NUTM1 sarcomas
| Â | Age (year) | Clinical site | Morphological characteristics | ETV4 | NUT | WT-1 | Mocecular | Survial(month) | |
|---|---|---|---|---|---|---|---|---|---|
CIC::NUTM1 sarcoma | 6 ~ 32 | Bone often | Solid and lobulated | + | + | Weak+ | CIC-NUTM1 gene fusion | 18.6mo | |
NUT middle carcinoma | 16 ~ 30 | upper aerodigestive tract | Solid and trabeculae | - | + | - | NUT-BRD1 gene fusion | 6.7mo | |
CIC gene rearranged sarcoma | 6 ~ 81 | Soft tissues | Solid and lobulated | + | - | -+ | CIC-DUX4 gene fusion | 139mo | |
Ewing sarcoma | Â <20 | Bone | Diffuse | - | - | - | EWSR1-FLI1/ERG gene fusion | Â 5-year survival rate over 90% | |