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Fig. 4 | Diagnostic Pathology

Fig. 4

From: Rare histologic transformation of a CTNNB1 (β-catenin) mutated prostate cancer with aggressive clinical course

Fig. 4

IHC staining for β-catenin in derived PDX (UB_PCa03) and two other Wnt-dependent established PDOs. Strong nuclear positivity for β-catenin staining is observed in the reported PDX UB-PCa03 (A), as well as in the established Wnt-dependent PDO WCM1078 (B). The neuroendocrine PDO PM154 (C) shows uniquely cytoplasmatic staining for β-catenin, as negative control

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Diagnostic Pathology

ISSN: 1746-1596

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