Fig. 5

Next-generation sequencing (NGS) and fluorescent in situ hybridization (FISH) for TMPRSS2/ERG rearrangement. (A) NGS (FoundationOne® CDx) results from liver metastatic biopsy. (B). FISH confirming presence of the ERG rearrangement in 92% of the analyzed cells on PDX histologic material. MS: microsatellite; TMB: tumor mutational burden