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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Immunohistochemistry staining of Eag1 and p16/Ki-67 can help improve the management of patients with cervical intraepithelial Neoplasia after cold knife conversion

Fig. 2

IHC score is correlated with CIN grade but not exactly corresponding. Eag1 staining corresponding Ki-67 and p16 stainings show positive predominantly found in the lower one-thirds of the epithelium (Score 1), which is most common in CIN1. Positive in the lower two-thirds of the epithelium (Score 2) is most common in CIN2. Positive in full-thickness of the epithelium (Score 2) is most common in CIN3+

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