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Table 2 Immunohistochemical expressions and TCR gene rearrangement of LL

From: Clinicopathological diagnosis of Lennert lymphoma: a case report and review of the literature

reference

Feller AC4

Geissinger E10

Hartmann S11

WeisenburgerD15

Kurita D9

Published year

1986

2004

2011

2011

2016

CD2

4/4(100)

10/18(56)

ND

13/13(100)

UK

CD3

4/4(100)

18/18(100)

8/8(100)

14/16(88)

26/26(100)

CD4

4/4(100)

1/18(6)

N/A

9/14(64)

22/26(85)

CD5

4/4(100)

17/18(94)

UK

13/15(87)

UK

CD8

0/4(0)

16/18(89)

3/8(38)

7/16(44)

5/26(19)

CD30Δ

ND

2/18(12)

5/8(63)

2/16(13)

UK

CD56

ND

0/18(0)

ND

1/13(8)

UK

TIA-1

N/A

N/A(53)

6/8(75)

6/13(46)

4/26(15)

GrB

N/A

N/A(35)

0/8(0)

UK

0/26(0)

TFH markers

ND

ND

0/8(0)

UK

15/26(58)

EBER

ND

ND

0/8(0)

4/13(31)

8/26(31)

Ki67

10-30%

UK

5-40%

UK

UK

TCRβ

4/4(100)※

UK

8/8(100)

10/11(91)

10/13(77)※

  1. Numbers are (positive cases / total cases, (%)); CD3E were used; positive numbers were evaluated by double staining of ki67 and each antibody; ΔCD30 expression was weak and limited to individual cells in cases regarded as positive; TFH markers consist of PD-1,CXCL13,CD10, and Bcl6, positivity for TFH markers was defined as neaplastic cells exhibiting > 20% staining for 1 or more of these markers; ※TCRβ, T-cell clonality was evaluated using T-cell receptor(TCR); ND, not done; N/A, indicates not available; UK, unknown