Table 1 Immunohistochemical staining results for IMP3, p53, and S100P in selected gallbladder lesions
IMP3 | p53 | S100P | IMP3/P53 | IMP3/P53/S100 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Negative/Weak | Positive | Wild-type | Aberrant | Negative/Weak | Positive | Non-double positive | Double positive | Non-triple positive | Triple positive | |
NL n(%) | 2 (100%) | 0 (0%) | 2 (100%) | 0 (0%) | 1 (50%) | 1 (50%) | 2 (100%) | 0 (0%) | 2 (100%) | 0 (0%) |
RA n(%) | 22 (75.9%) | 7 (24.1%) | 26 (89.7%) | 3 (10.3%) | 2 (6.9%) | 27 (93.1%) | 27 (93.1%) | 2 (6.9%) | 27 (93.1%) | 2 (6.9%) |
LGD n(%) | 7 (43.7%) | 9 (56.3%) | 8 (50%) | 8 (50%) | 0 (0%) | 16 (100%) | 12 (75%) | 4 (25%) | 12 (75%) | 4 (25%) |
HGD n(%) | 0 (0%) | 2 (100%) | 1 (50%) | 1 (50%) | 0 (0%) | 2 (100%) | 1 (50%) | 1 (50%) | 1(50%) | 1(50%) |
IAC n(%) | 1 (20%) | 4 (80%) | 0 (0%) | 5 (100%) | 0 (0%) | 5 (100%) | 1 (20%) | 4 (80%) | 1 (20%) | 4 (80%) |
p-value RA vs. LGD | 0.03 | 0.003 | 0.3 | 0.09 | 0.09 | |||||
p-value RA vs. LGD + HGD | 0.01 | 0.002 | 0.3 | 0.05 | 0.05 | |||||