Fig. 3

A left intraorbital EMZL and marrow involvement in case 2. (A) Small to medium-sized lymphoid cell diffuse infiltration with vaguely nodular distribution, separated by fibrous septa of varying thickness (H&E, ×4). (B) A mix of centrocyte-like cells, monocytoid B cells, and small lymphocyte-like cells (H&E, ×20). (C) Neoplastic cells were negative for bcl6 (En Vision, × 20); Inset: Diffuse positivity for CD20 (En Vision, × 10). (D) Small lymphoid cells with monocytoid B cells appearance exhibiting a paratrabecular infiltrate (H&E, ×4). (E) Neoplastic cells were strongly positive for CD20 (En Vision, × 20). (F) Neoplastic cells were weakly positive for bcl6 (En Vision, × 40)