Table 5 The univariate and multivariate analyses of OS according to the clinicopathological variables and the expression of SGLT2 and PRDX4

Sex

12.313

1.233–65.357

0.966

Age

11.304

2.350-59.275

0.164

Maximal tumor diameter (cm)

16.731

1.769–55.326

0.103

Serum AFP (ng/ml)

5.342

1.529–12.370

0.338

PRETEXT stage

2.453

0.882–4.324

0.047

Metastasis

21.320

3.527–59.306

< 0.001

Histological category

6.654

2.527–16.832

0.112

SGLT2 IHC index

2.211

1.267–4.393

0.039

PRDX4 IHC index

7.447

1.745–17.432

0.006

Low-SGLT2 with high-PRDX4

8.739

3.561–23.356

< 0.001

PRETEXT stage

2.378

0.772–4.225

< 0.001

Metastasis

22.436

3.121–54.381

0.029

SGLT2 IHC index

1.993

1.102–4.117

0.041

PRDX4 IHC index

7.779

1.643–18.305

< 0.001

Low-SGLT2 with high-PRDX4

9.675

2.343–22.765

< 0.001