Immunohistochemical expression of parathyroid hormone-related protein and ezrin in invasive breast carcinoma of no special type: a retrospective analysis

Table 3 Comparison of ezrin expression in different studied groups

Ezrin		Control (n = 37)		Adjacent DCIS (n = 31)		IBC (n = 123)		Test of Sig. (p)
Ezrin		No.	%	No.	%	No.	%	Test of Sig. (p)
Expression	Negative	15	40.5	0	0.0	9	7.3	χ²= 27.323^* (^MCp (< 0.001^*)
Expression	Positive	22	59.5	31	100.0	114	92.7	χ²= 27.323^* (^MCp (< 0.001^*)
Percent	Min. – Max.	45.0–80.0		60.0–90.0		60.0–90.0		H = 48.930^* (< 0.001^*)
	Mean ± SD.	67.05 ± 8.95		67.74 ± 8.25		79.25 ± 8.15
	Median (IQR)	70.0 (60.0–75.0)		70.0 (60.0–70.0)		80.0 (70.0–90.0)
H score	Min. – Max.	55.0–140.0		60.0–240.0		70.0–270.0		H = 61.786^* (< 0.001^*)
	Mean ± SD.	75.23 ± 22.70		157.4 ± 46.0		200.4 ± 53.13
	Median (IQR)	70.0 (60.0–80.0)		160.0 (130.0–180.0)		210.0 (160.0–240.0)

IQR: Inter quartile range SD: Standard deviation H: H for Kruskal Wallis test
χ²: Chi square test MC: Monte Carlo test
p: p value for comparing different studied groups
*: Statistically significant at p ≤ 0.05

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