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Table 1 Clinicopathologic characteristics of papillary thyroid carcinoma patients with TERT promoter mutation

From: The impact of C216T and hot spot mutations of the TERT promoter on the clinicopathologic characteristics and S100A10 expression in papillary thyroid carcinoma: a comparative study

Case No.

TERT promoter mutation

Age (yr)

Sex

Tumor size (cm)

Histologic variant

Multifocality

Vascular invasion

Extrathyroidal

extension

Hashimoto’s thyroiditis

ATA recurrence risk

AJCC staging

BRAF V600E mutation

pT

pN

M

Stage

1

C228T

58

Male

1.5

Classic

N

N

None

N

Intermediate

1

1

0

2

Present

2

C228T

58

Female

1.4

Classic

N

N

Minimal

N

Intermediate

1

1

0

1

Present

3

C228T

77

Male

2.5

Classic

Y

Y

Minimal

N

High

2

1

0

2

Present

4

C228T

63

Female

2.4

Tall cell

N

N

Minimal

N

Intermediate

2

0

0

1

None

5

C228T

67

Female

2.1

Classic

Y

N

Minimal

N

Intermediate

2

1

0

2

Present

6

C228T

64

Female

0.9

Tall cell

Y

N

Minimal

N

Intermediate

1

1

0

2

Present

7

C228T

63

Female

5.0

Classic

N

N

Gross

N

High

3

1

0

2

Present

8

C228T

65

Female

2.4

Classic

N

Y

Minimal

N

High

2

1

0

2

Present

9

C228T

56

Female

4.2

Tall cell

N

N

Gross

N

High

3

1

0

2

Present

10

C228T

37

Male

0.7

Classic

Y

N

None

N

Intermediate

1

1

0

1

Present

11

C250T

51

Male

2.3

Classic

Y

N

Minimal

N

High

2

1

0

1

Present

12

C228T

52

Male

1.7

Classic

N

N

Minimal

N

Intermediate

1

1

0

1

None

13

C216T

30

Male

0.6

Classic

N

N

None

N

Low

1

0

0

1

Present

14

C216T

50

Female

0.6

Classic

N

N

None

N

Low

1

1

0

1

Present

15

C216T

37

Female

0.3

Classic

N

N

None

N

Low

1

0

0

1

Present

16#

C216T

69

Female

0.6

Classic

NA

N

None

NA

NA

1

NA

NA

NA

Present

17*

C216T

44

Female

0.4

Classic

N

NA

None

NA

Low

1

0

0

1

Present

18*

C216T

55

Female

0.5

Classic

N

NA

None

NA

Low

1

0

0

1

Present

19*

C216T

29

Male

1.0

Classic

Y

NA

Minimal

NA

Intermediate

1

1

0

1

Present

20*

C216T

54

Male

1.2

Classic

N

NA

Minimal

NA

Intermediate

1

0

0

1

Present

  1. Y, yes; N, no; NA, not available; # enrolled from the reference 15; * enrolled from the reference 16