Fig. 3
From: Trichorhinophalangeal syndrome type 1 (TRPS1) in breast pathology: diagnostic utility and pitfalls
Metastatic serous carcinoma of tubo-ovarian origin to breast with TPRS1, GATA3, PAX8, and WT1 immunostaining. 3A: H & E-stained section at 20X magnification showing a breast core with invasive carcinoma. 3B: H & E-stained section at 50X revealing papillary growth pattern. 3C: TRPS1 immunostaining at 50X magnification showing moderate nuclear staining. 3D: GATA3 immunostaining revealing patchy moderate staining. 3E: PAX8 immunostaining at 50X depicting strong nuclear staining. 3F: WT1 immunostaining at 50X revealing strong diffuse nuclear staining consistent with tubo-ovarian primary origin