Table 6 Association of TRPS1 expression with biomarker profile and pathological features
From: Trichorhinophalangeal syndrome type 1 (TRPS1) in breast pathology: diagnostic utility and pitfalls
Biomarkers and pathological features | TRPS1, n (%) | p-value | |
|---|---|---|---|
Positive | Negative | ||
ER (n = 97) |  |  |  |
Positive | 37 (42.0) | 1 (11.1) | 0.085 |
Negative | 51 (58.0) | 8 (88.9) | Â |
PR (n = 94) |  |  |  |
Positive | 19 (21.8) | 0 (0) | 0.338 |
Negative | 68 (78.2) | 7 (100) | Â |
HER2neu (n = 89) |  |  |  |
Positive | 5 (6) | 0 (0) | 1.000 |
Negative | 79 (94) | 5 (100) | Â |
Tumor type (n = 84) * |  |  |  |
Ductal | 65 (83.3) | 5 (83.3) | 0.194 |
Lobular | 2 (2.6) | 0 (0) | Â |
Metaplastic | 7 (9) | 0 (0) | Â |
Micropapillary | 3 (3.8) | 0 (0) | Â |
Others | 1 (1.3) | 1 (16.7) | Â |
Tumor grade (n = 84) * |  |  |  |
Low-intermediate | 24 (30.8) | 3 (50) | 0.381 |
High | 54 (69.2) | 3 (50) | Â |