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Table 1 Baseline characteristics of male and female breast cancer

From: Redefining therapeutic landscapes: clinicopathological insights into low and ultra-low HER2 expression in male breast cancer

Demographics

Total(n =199 )

Male(n =106 )

Female(n = 93)

χ2

P Value*

Age

     

<60 years

81

28 (26.42%)

53 (56.99%)

19.186

0.000*

≥ 60 years

118

78 (73.58%)

40 (43.01%)

  

Laterality

     

Right

97

46 (43.40%)

51 (54.84%)

2.660

0.264

Left

100

59 (55.66%)

41 (44.09%)

  

Other

2

1 (0.94%)

1 (1.08%)

  

Maximum tumor diameter

   

<2

52

32 (30.19%)

20 (21.51%)

4.117

0.128

≥ 2

139

72 (67.92%)

67 (72.04%)

  

Other

8

2 (1.89%)

6 (6.45%)

  

Lymph node metastases

   

Yes

73

42 (39.62%)

31 (33.33%)

0.8448

0.358

No

126

64 (60.38%)

62 (66.67%)

  

HER2

     

0

48

23(21.69%)

25 (26.88%)

6.675

0.036*

Low

120

72 (67.93%)

48 (51.61%)

  

Positive

31

11 (10.38%)

20 (21.51%)

  

HER2

     

0

48

23(21.70%)

25 (26.88%)

16.483

0.002*

1+

55

27 (24.47%)

28 (30.11%)

  

2 + ISH -

65

45 (42.45%)

20 (21.51%)

  

2 + ISH +

9

6(5.66%)

3 (3.23%)

  

3+

22

5(4.72%)

17 (18.28%)

  

Estrogen Receptor, ER

   

Negative

27

7 (6.60%)

16 (17.20%)

5.446

0.026*

Positive

172

99 (93.40%)

77 (82.80%)

  

Progestogen Receptor, PR

   

Negative

32

8 (7.55%)

19 (20.43%)

7.011

0.008*

Positive

167

98(92.45%)

74 (79.57%)

  

Ki-67

     

<14%

34

19 (17.92%)

15 (16.13%)

0.113

0.737

≥ 14%

165

87 (82.08%)

78 (83.87%)