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Table 7 Univariate cox regression analysis of factors influencing recurrence in overall patients

From: Exploration of risk factors for the occurrence and recurrence of papillary thyroid carcinoma with Hashimoto's thyroiditis based on next-generation sequencing

Characteristics

β

SE

Wald 

P

HR (95% CI)

Age

0.182

0.469

0.150

0.698

1.200 (0.478~3.009)

Sex

0.034

0.019

3.206

0.073

1.035 (0.997~1.074)

Tumor Diameter (cm)

0.134

0.255

0.274

0.601

1.143 (0.693~1.885)

Multifocal

1.615

0.469

11.858

0.001

5.027 (2.005~12.604)

LNM

1.780

0.627

8.058

0.005

5.927 (1.735~20.250)

ETE

3.159

0.518

37.248

0.000

23.554 (8.540~64.967)

Recurrence risk Stage

     

 1

  

35.364

0.000

 

 2

2.955

0.659

20.140

0.000

19.208 (5.284~69.826)

 3

4.117

0.693

35.326

0.000

61.352 (15.786~238.448)

TSH

0.038

0.010

14.977

0.000

1.039 (1.019~1.059)

Coexistence with HT

-0.644

0.745

0.746

0.388

0.525 (0.122~2.264)

BRAF Mutation

0.691

0.560

1.523

0.217

1.995 (0.666~5.977)

RET Rearrangement

1.248

0.562

4.928

0.026

3.483 (1.157~10.484)

RET Rearrangement * Coexistence with HT

1.608

0.747

4.631

0.031

4.991 (1.154~21.585)

BRAF Mutation * Coexistence with HT

-0.659

1.026

0.412

0.521

0.518 (0.069~3.866)

BRAF Mutation * RET Rearrangement

1.755

1.032

2.893

0.089

5.783 (0.766~43.682)

  1. ETE Extrathyroidal extension, LNM Lymph node metastasis, HT Hashimoto's thyroiditis