CD200 in acute myeloid leukemia: marked upregulation in CEBPA biallelic mutated cases

Diagnostic Pathology

Table 1 Markers associated with CD200 expression in AML

	Positive cases/total cases MFI ± SD*	Correlation coefficient with CD200 MFI	p-value
CD34+	127/431 166.7 ± 147.1	0.650	< 0.001
HLA-DR+	208/431 1312.9 ± 1321.4	0.502	< 0.001
CD13+	203/431 217.1 ± 546.4	0.492	< 0.001
CD117+	255/431 122.4 ± 90.5	0.488	< 0.001
CD71+	202/431 55.0 ± 117.9	0.456	< 0.001
CD123+	238/431 127.8 ± 108.4	0.428	< 0.001
CD38+	205/431 48.7 ± 35.7	0.402	< 0.001

AML, acute myeloid leukemia; *MFI ± SD, mean MFI of each marker in positive cases ± Standard derivation. MFI, mean fluorescence intensity. CD15+, CD7+, CD36+, CD64+, and CD33 + also showed statistically significant correlations; however, their correlation coefficients with CD200 MFI were all below 0.4

ISSN: 1746-1596