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Table 2 Univariate and multivariate Cox regression analyses about the potential prognostic factors for disease-free survival in patients with invasive PDAC and IPMC

From: Long-chain fatty acyl CoA synthetase 4 expression in pancreatic cancer: a marker for malignant lesions and prognostic indicator for recurrence

   

Univariate analysis

 

Multivariate analysis

Characteristics

n

HR

(95%Cl)

p

 

HR

(95%Cl)

p

ACSL4 expression

        
 

 High

82

1

      
 

 Low

13

2.533

(1.283–5.004)

0.007

 

2.409

(1.121–5.180)

0.024

Age

        
 

 < 70

30

1

      
 

 ≧ 70

66

1.032

(0.589–1.808)

0.913

    

Sex

        
 

 Male

57

1

      
 

 Female

39

0.891

(0.679–1.170)

0.405

    

Location

        
 

 Pbt

43

1

      
 

 Ph

53

1

(0.765–1.307)

0.999

 

0.684

(0.370–1.265)

0.226

Histology

        
 

 Well ~ mod

90

1

      
 

 Por

6

0.714

(0.257–1.984)

0.518

 

0.478

(0.152–1.503)

0.207

pT

        
 

 T1

10

1

      
 

 ≧T2

86

0.916

(0.599–1.402)

0.687

    

Size (mm)

        
 

 < 30

64

1

      
 

 ≧ 30

32

1.674

(0.963–2.912)

0.068

 

1.543

(0.811–2.937)

0.187

LN metastasis

        
 

 -

51

1

      
 

 +

45

1.4

(0.819–2.392)

0.216

 

0.992

(0.528–1.862)

0.979

Lymphatic invasion

        
 

 -

21

1

      
 

 +

75

2.333

(1.100-4.949)

0.027

 

1.577

(0.563–4.416)

0.408

Vascular invasion

        
 

 -

39

1

      
 

 +

57

2.156

(1.199–3.878)

0.01

 

1.902

(0.843–4.292)

0.119

Neuro invasion

        
 

 -

27

1

      
 

 +

69

1.235

(0.672–2.272)

0.496

 

0.562

(0.262–1.207)

0.341

Margins

        
 

  -

81

1

      
 

 +

15

1.388

(0.697–2.762)

0.349

 

0.946

(0.431–2.076)

0.89

Neoadjuvant chemotherapy

        
 

 -

66

1

      
 

 +

30

0.829

(0.450–1.529)

0.548

    

Adjuvant chemotherapy

        
 

 -

25

1

      
 

 +

71

1.12

(0.589–2.129)

0.73

 

1.484

(0.751–2.930)

0.256

CA19-9

        
 

 < 37

42

1

      
 

 ≧ 37

54

1.712

(0.987–2.972)

0.056

 

1.655

(0.898–3.050)

0.107