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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Benign nerve sheath tumors (BNSTs) present diagnostic challenges due to their heterogeneous nature. This study aimed to determine the significance of NRG1 as a novel diagnostic biomarker in BNST, emphasizing i...

    Authors: Suwei Yan, Jingnan Zhao, Pengyang Gao, Zhaoxu Li, Zhao Li, Xiaobing Liu and Pengfei Wang
    Citation: Diagnostic Pathology 2024 19:28
  2. NUT carcinoma is a rare cancer associated with a poor prognosis. Because of its rarity, its diagnosis is challenging and is usually made by excluding other diagnoses. Immunohistochemical analysis is a reliable...

    Authors: Hironori Ninomiya, Yukiko Sato, Kentaro Inamura, Akito Dobashi, Kengo Takeuchi, Hiroki Mitani, Mingyon Mun, Makoto Nishio and Yuichi Ishikawa
    Citation: Diagnostic Pathology 2024 19:27
  3. Differences in the preparation, staining and scanning of digital pathology slides create significant pre-analytic variability. Algorithm-assisted tools must be able to contend with this variability in order to...

    Authors: Ariel Greenberg, Benzion Samueli, Shai Farkash, Yaniv Zohar, Shahar Ish-Shalom, Rami R. Hagege and Dov Hershkovitz
    Citation: Diagnostic Pathology 2024 19:26
  4. Multiple primary malignancies are rare in cancer patients, and risk factors may include genetics, viral infection, smoking, radiation, and other environmental factors. Lynch syndrome (LS) is the most prevalent...

    Authors: Tiansong Zhang, Xiaoqiang Huang, Wenjie Liu, Xiulan Ling, Zhenping Su, Mengwei Huang and Shuanlong Che
    Citation: Diagnostic Pathology 2024 19:25
  5. Follicular dendritic cell sarcoma (FDCS) is a rare low-grade tumor of the lymph nodes, but roughly one-third of the cases emerge from extranodal sites, posing diagnostic challenges.

    Authors: Tamás Pancsa, Borbála Dénes, Áron Somorácz, Dóra Kelemen, Ferenc Salamon, Fanni Sánta and Levente Kuthi
    Citation: Diagnostic Pathology 2024 19:24
  6. Chronic myeloid leukemia (CML) is characterized by the presence of BCR::ABL1 fusion gene resulting from a reciprocal translocation, t(9;22)(q34;q11.2), leading to prominent granulocytic proliferation. The majorit...

    Authors: Michelle Hyunju Lee, Amy Song and Julie Y. Li
    Citation: Diagnostic Pathology 2024 19:21
  7. Giant cell-rich solitary fibrous tumour (GCR-SFT), previously referred to as giant cell angiofibroma, is an uncommon soft tissue tumour that classically occurs in the orbit but very rarely presents in deep org...

    Authors: Zhou Su, Jianguo Wei and Xiaolu Yuan
    Citation: Diagnostic Pathology 2024 19:20
  8. EWSR1::NFATC2 rearranged sarcomas are a group of rare round, undifferentiated sarcomas with clinicopathological features different from those of Ewing's sarcoma (ES) family and other non-ES sarcomas. We report 4 ...

    Authors: Lili Liu, Lan Li, Yi Ding, Fangzhou Kong, Wenfa Mo, Hongtao Ye and Danhua Shen
    Citation: Diagnostic Pathology 2024 19:19
  9. Breast cancer is the most common malignant tumor in the world. Intraoperative frozen section of sentinel lymph nodes is an important basis for determining whether axillary lymph node dissection is required for...

    Authors: Zuxuan Zhao, Cancan Chen, Hanwen Guan, Lei Guo, Wanxin Tian, Xiaoqi Liu, Huijuan Zhang, Jiangtao Li, Tinglin Qiu, Jun Du, Qiang Guo, Fenglong Sun, Shan Zheng and Jianhui Ma
    Citation: Diagnostic Pathology 2024 19:18
  10. c-MYC and BCL2 positivity are important prognostic factors for diffuse large B-cell lymphoma. However, manual quantification is subject to significant intra- and inter-observer variability. We developed an aut...

    Authors: Thomas E. Tavolara, M. Khalid Khan Niazi, Andrew L. Feldman, David L. Jaye, Christopher Flowers, Lee A.D. Cooper and Metin N. Gurcan
    Citation: Diagnostic Pathology 2024 19:17
  11. Epithelioid angiomyolipoma (EAML) is a rare variant of angiomyolipoma that predominantly consists of epithelioid cells and belongs to the perivascular epithelioid cell neoplasm (PEComa) family. The majority of...

    Authors: Yaewon Yang, Jisun Lee, Chang Gok Woo, Ok-Jun Lee and Seung-Myoung Son
    Citation: Diagnostic Pathology 2024 19:16
  12. Mammary mucoepidermoid carcinoma (MEC) is a rare entity. The molecular characteristics of breast MEC have not been fully investigated due to its rarity. We performed a retrospective study among 1000 patients w...

    Authors: Yan Ge, Xingtao Lin, Jiao He, Wendan Chen, Danyi Lin, Yihong Zheng, Lingling Yang, Fangping Xu and Zhi Li
    Citation: Diagnostic Pathology 2024 19:15
  13. Histiocytic necrotizing lymphadenitis (HNL) is a benign, self-limiting disease that is rare clinically. The coexistence of HNL and tumor is rarer. We report a male patient who was preoperatively diagnosed with...

    Authors: Jing Liu, Lei Jiang, Guohua Yu, Guimei Qu and Li Cai
    Citation: Diagnostic Pathology 2024 19:14
  14. Prostein (P501S), also termed solute carrier family 45 member 3 (SLC45A3) is an androgen regulated protein which is preferentially expressed in prostate epithelial cells. Because of its frequent expression in ...

    Authors: Florian Viehweger, Carola Böcker, Sören Weidemann, Morton Freytag, Anne Menz, Franziska Büscheck, Andreas M. Luebke, Devita Putri, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch, Maximilian Lennartz, Florian Lutz, Viktor Reiswich, Doris Höflmayer, Christoph Fraune…
    Citation: Diagnostic Pathology 2024 19:12
  15. Despite major advancements, effective treatment for patients with SMARCB1-deficient cancers has remained elusive. Here, we report the first case of a SMARCB1-deficient undifferentiated carcinoma in the rectum...

    Authors: Wenjuan Shen, Yi Pan and Shuangmei Zou
    Citation: Diagnostic Pathology 2024 19:11
  16. Actionable, solid tumor activating neurotrophic receptor tyrosine kinase (NTRK) fusions are best detected via nucleic acid-based assays, while Pan-TRK immunohistochemistry (IHC) serves as a reasonable screening m...

    Authors: Cansu Karakas, Ellen J. Giampoli, Tanzy Love, David G. Hicks and Moises J. Velez
    Citation: Diagnostic Pathology 2024 19:10
  17. Deleterious mutations in the BRCA1 and BRCA2 genes have significant therapeutic relevance in clinical settings regarding personalized therapy approaches. BRCA1 and BRCA2 play a pivotal role in homologous recombin...

    Authors: Anne Vogel, Anna Haupts, Michael Kloth, Wilfried Roth and Nils Hartmann
    Citation: Diagnostic Pathology 2024 19:9
  18. Cutaneous Melanocytic Tumor with CRTC1::TRIM11 Fusion (CMTCT) represents a novel and rare entity in the realm of dermatological oncology, characterized by distinct melanocytic differentiation. This particular tum...

    Authors: Rong Duan, Xiaojuan He, Xiaojing Ma, Fengbo Huang and Xiangrong Hu
    Citation: Diagnostic Pathology 2024 19:8
  19. We encountered a cervical lymphoepithelial carcinoma (LEC) possessing a predominantly solid architecture with deficient mismatch repair (dMMR) and loss of expression of the SWI/SNF (SWItch/Sucrose Non-Fermenta...

    Authors: Yu Miyama, Tomomi Kato, Masayasu Sato, Akira Yabuno, Kosei Hasegawa and Masanori Yasuda
    Citation: Diagnostic Pathology 2024 19:6
  20. The status of hormone receptors (HR) is an independent factor affecting survival and chemotherapy sensitivity in breast cancer (BC) patients, with estrogen receptor (ER) and progesterone receptor (PR) having t...

    Authors: He Dou, Fucheng Li, Youyu Wang, Xingyan Chen, Pingyang Yu, Siyuan Jia, Yuling Ba, Danli Luo, Tian Gao, Zhaoting Li and Min Xiao
    Citation: Diagnostic Pathology 2024 19:5
  21. Ovarian cancer is the deadliest gynecologic cancer due to its high rate of recurrence and limited early diagnosis. For certain patients, particularly those with recurring disorders, standard treatment alone is...

    Authors: Tingchuan Xiong, Yinghong Wang and Changjun Zhu
    Citation: Diagnostic Pathology 2024 19:4
  22. We previously described a series of cases which characterize a distinct group of primary ovarian placental site trophoblastic tumor (PSTT) and epithelioid trophoblastic tumor (ETT) as a non-gestational set con...

    Authors: Maryam Shahi, Levon Katsakhyan, Mark Hopkins, Wendy Allen-Rhoades, Marissa K. Cepress, Carrie Langstraat, Michael B. Ishitani, Russell Vang, Brigitte M. Ronnett and Deyin Xing
    Citation: Diagnostic Pathology 2024 19:3
  23. Benign metastasizing leiomyoma (BML) is a rare disease with an unknown etiopathogenesis that mostly affects middle-aged women with uterine leiomyoma. Many metastatic nodules outside the uterus characterize the...

    Authors: Aziz Chouchane, Sassi Boughizane, Monia Nouira and Sami Remadi
    Citation: Diagnostic Pathology 2024 19:2
  24. NRG1 fusion is a promising therapeutic target for various tumors but its prevalence is extremely low, and there are no standardized testing algorithms for genetic assessment.

    Authors: Xiaomei Zhang, Lin Li, Fuping Gao, Binbin Liu, Jing Li, Shuang Ren, Shuangshuang Peng, Wei Qiu, Xiaohong Pu and Qing Ye
    Citation: Diagnostic Pathology 2024 19:1
  25. A marked increase in PD1-positive TFH cells in nodal MZL cases (NMZL) was reported previously and could prompt suspicion for a diagnosis of peripheral T-cell lymphoma (PTCL), especially angioimmunoblastic T-ce...

    Authors: Jili Deng, Youjun Cao, Xinting Diao, Meng Wu, Xianghong Li and Yunfei Shi
    Citation: Diagnostic Pathology 2023 18:134
  26. In adults with non-Hodgkin's lymphoma, renal enlargement and acute kidney injury occur infrequently at first presentation, especially in T lymphocytic lymphomas.

    Authors: Yu Bai, Yuanyuan Zheng, Qidong Zhang, Qun Jiang, Zongli Diao, Wang Guo, Sha Liu and Wenhu Liu
    Citation: Diagnostic Pathology 2023 18:133
  27. PD-L1 staining using long-stored paraffin sections may not be consistent with the true PD-L1 expression of patients. Therefore, it is necessary to explore the expression of PD-L1(SP142) in paraffin sections of...

    Authors: Jiankun He, Xinran Wang, Lijing Cai, Zhanli Jia, Chang Liu, Xuemei Sun, Si Wu, Chunyan Ding, Zi Zhang and Yueping Liu
    Citation: Diagnostic Pathology 2023 18:131
  28. Authors: Anna-Leonie Menges, Maja Nackenhorst, Johannes R. Müller, Marie-Luise Engl, Renate Hegenloh, Jaroslav Pelisek, Ellen Geibelt, Anja Hofmann, Christian Reeps, Gabor Biro, Hans-Henning Eckstein, Alexander Zimmermann, Derek Magee, Martin Falk, Nadja Sachs and Albert Busch
    Citation: Diagnostic Pathology 2023 18:130

    The original article was published in Diagnostic Pathology 2023 18:73

  29. To investigate the expression of polo-like kinase 1 protein (PLK1) and its phosphorylation level (p-PLK1) in extranodal NK/T cell lymphoma (NKTCL) and their correlation with clinical characteristics and progno...

    Authors: Zhiqi Zhang, Enjie Liu, Dandan Zhang, Wugan Zhao, Guannan Wang, Yanping Zhang, Yajun Huo, Chongli Zhang and Wencai Li
    Citation: Diagnostic Pathology 2023 18:129
  30. The study of pathologic diagnosis of placental TB is rare. The aim of this study is analyzing the pathomorphological characteristics of tuberculosis (TB) placenta during pregnancy and its clinical significance.

    Authors: Zhidong Hu, Dong Zeng, Yuexiang Yang, Huijun Liu, Ao Wang, Duoduo Li, Min Liu and Yanling Feng
    Citation: Diagnostic Pathology 2023 18:128
  31. Neuroblastoma is rare in the adult population, especially in thoracic or mediastinal locations, with only 25 previously reported cases. We report an additional example of primary thymic neuroblastoma in a prev...

    Authors: Katrina Collins, Thomas M. Ulbright and Jessica L. Davis
    Citation: Diagnostic Pathology 2023 18:127
  32. Overlapping morphological features of mesothelial cells have been rendered it difficult to distinguish between reactive and malignant conditions. The development of methods based on detecting genomic abnormali...

    Authors: Miho Yoshida, Naoe Jimbo, Ryuko Tsukamoto, Tomoo Itoh, Kunimitsu Kawahara, Suguru Mitsui, Yugo Tanaka and Yoshimasa Maniwa
    Citation: Diagnostic Pathology 2023 18:126
  33. The association of human herpesvirus 6 (HHV-6) species with pancreatic cancer is controversially discussed. The aim of this study was to further investigate the postulated association and to identify the basis...

    Authors: S. Warkentin, T. A. Braunschweig, D. Jonigk, I. Losen, M. A. Cassataro and M. Kleines
    Citation: Diagnostic Pathology 2023 18:124
  34. With the continuous discovery of new borderline thyroid lesions and benign and malignant “gray areas”, coupled with the limitations of traditional immune indicators, the differential diagnosis of papillary thy...

    Authors: Chen-chen Wang, Dan-dan Lu, Ming-hong Shen, Ru-lei Chen, Zhi-hong Zhang and Jing-huan Lv
    Citation: Diagnostic Pathology 2023 18:123
  35. Histologic evaluation of the mucosal changes associated with celiac disease is important for establishing an accurate diagnosis and monitoring the impact of investigational therapies. While the Marsh-Oberhuber...

    Authors: Aaron M. Gruver, Haiyan Lu, Xiaoxian Zhao, Angie D. Fulford, Michael D. Soper, Darryl Ballard, Jeffrey C. Hanson, Andrew E. Schade, Eric D. Hsi, Klaus Gottlieb and Kelly M. Credille
    Citation: Diagnostic Pathology 2023 18:122
  36. Although neural networks have shown remarkable performance in medical image analysis, their translation into clinical practice remains difficult due to their lack of interpretability. An emerging field that ad...

    Authors: Marion Dörrich, Markus Hecht, Rainer Fietkau, Arndt Hartmann, Heinrich Iro, Antoniu-Oreste Gostian, Markus Eckstein and Andreas M. Kist
    Citation: Diagnostic Pathology 2023 18:121
  37. Renal transplant recipients (RTRs) have a 3- to 5-fold higher risk of developing malignant tumors than the general population, with new malignant tumors after transplantation considered to be the leading cause...

    Authors: Daosheng Li, Fenfen Liu, Yiqian Chen, Ping Li, Yuyu Liu and Yu Pang
    Citation: Diagnostic Pathology 2023 18:120
  38. DNA damage response and repair (DDR) genes are crucial for maintaining the integrity of the genome. This study aims to explore the correlation of DDR gene mutations with TMB, clinical characteristics, and outc...

    Authors: Weiguang Gu, Wenya Zhuang, Mengxia Zhuang, Minhong He and Zhihua Li
    Citation: Diagnostic Pathology 2023 18:119
  39. Nevoid basal cell carcinoma syndrome (NBCCS, Gorlin syndrome) is a rare autosomal dominantly inherited disorder that is characterized by multisystem disorder such as basal cell carcinomas, keratocystic odontog...

    Authors: Menghan Zhu, Jun Li, Jie Duan, Jing Yang, Weiyong Gu and Wei Jiang
    Citation: Diagnostic Pathology 2023 18:118
  40. Penile melanoma (PM) is a rare tumor, accounting for less than 2% of all penile cancers. PM can occur on the surface of the glans, foreskin, and opening of the urethra. Furthermore, PM primarily affects older ...

    Authors: Boglárka Pósfai, Márton Szentkereszty, Fanni Sánta, Zoltán Bajory, Andrea Simon, Zsófia Kozéki, Ildikó Csányi, Mahmut Akgul and Levente Kuthi
    Citation: Diagnostic Pathology 2023 18:117
  41. Among the three NTRK genes, NTRK2 possesses a tremendous structural complexity and involves tumorigenesis of several types of tumors. To date, only STRN and RBPMS are identified in the fusion with NTRK2 in adult ...

    Authors: Ruihe Lin, Atrayee Basu Mallick, Zi-Xuan Wang, Scot Andrew Brown, Bo Lu and Wei Jiang
    Citation: Diagnostic Pathology 2023 18:116
  42. Adult non-neoplastic hyperinsulinemic hypoglycemia (ANHH), also known as adult-onset nesidioblastosis, is a rare cause of endogenous hyperinsulinemic hypoglycemia in adults. This disease is characterized by di...

    Authors: Ryota Nakagawa, Sachiko Minamiguchi, Tatsuki R. Kataoka, Junji Fujikura, Toshihiko Masui, Masakazu Fujimoto, Yosuke Yamada, Yasuhide Takeuchi, Yuki Teramoto, Hiroaki Ito, Manduwa Saka, Kyohei Kitamura, Shinya Otsuki, Ryohei Nishijima and Hironori Haga
    Citation: Diagnostic Pathology 2023 18:115
  43. Disease from Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) remains the seventh leading cause of death in the United States. Many patients infected with this virus develop later cardiovascular co...

    Authors: Margo E. Hammond, Erik D. Christensen, Michael Belenky, Gregory L. Snow, Kevin Shah and M. Elizabeth H. Hammond
    Citation: Diagnostic Pathology 2023 18:114
  44. Invasive stratified mucin-producing carcinoma is a recently recognized adenocarcinoma with distinctive features. It was first described in the cervix but similar tumors have since been reported in the penis, a...

    Authors: Finn Morgan Auld and Terence N. Moyana
    Citation: Diagnostic Pathology 2023 18:113

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