Fig. 2

Histological appearance of perinephric myxoid pseudotumor of fat

(A-C) Renal parenchyma shows the picture of an end-stage-kidney with sclerosis of the glomeruli, interstitial fibrosis and tubular atrophy (✱). PMPF is directly adjacent to the renal capsule (▼) (HE, scale bar = 250 μm). (D-F) PMPF consists of an admixture of mature fat, fibromyxoid stroma and spindled to stellate stromal cells with a variably intense mixed inflammatory cell infiltrate (HE, scale bar = 100 μm). (G-J) Spindled to stellate cells of PMPF without cytological atypia (HE, scale bar = 50 μm). (K-M) MDM2 fluorescence in situ hybridization: No amplification of the MDM2 gene in all three cases (scale bar = 10 μm).