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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Distinguishing reactive atypia from dysplasia in cholecystectomy specimens can be histologically challenging. The aim of this study was to evaluate the utility of IMP3, p53, and S100P immunostains in different...

    Authors: Evan Sica, Karen T. Shore, Limin Yang, Kara Chan Phelps, Suntrea T. G. Hammer, Purva Gopal, Dipti M. Karamchandani and James Michael Mitchell
    Citation: Diagnostic Pathology 2024 19:129
  2. Oral nicotine pouches are the latest products in the tobacco industry. They are manufactured by large tobacco companies and entice tobacco or nicotine addicts, although the products are presented as a ‘harmles...

    Authors: Sintija Miluna-Meldere, Sarlote Agate Vanka, Ingus Skadins, Juta Kroica, Maris Sperga and Dagnija Rostoka
    Citation: Diagnostic Pathology 2024 19:127

    The Correction to this article has been published in Diagnostic Pathology 2025 20:12

  3. Submucosal pseudoinvasion and squamous metaplasia (SM) are incidental and special morphological findings in colorectal adenomas, and both can mimic invasive carcinoma. The coexistence of these two findings fur...

    Authors: Li Shi, Huamin Li, Shulian Li, Songyan Lin and Ying Wu
    Citation: Diagnostic Pathology 2024 19:126
  4. Colorectal cancer (CRC) constitutes around 10% of global cancer diagnoses and death due to cancer. Treatment involves the surgical resection of the tumor and regional lymph nodes. Assessment of multiple lymph ...

    Authors: Talat Zehra, Sarosh Moeen, Mahin Shams, Muhammad Raza, Amna Khurshid, Asad Jafri and Jamshid Abdul-Ghafar
    Citation: Diagnostic Pathology 2024 19:125
  5. Grade 3 neuroendocrine tumor (G3 PanNET) and poorly differentiated neuroendocrine carcinoma (PanNEC) of the pancreas are considered distinct entities from a biological and prognostic perspective but may have o...

    Authors: Brooke Mullen, Albert L. Sy, Priscila Dias Goncalves and M. Lisa Zhang
    Citation: Diagnostic Pathology 2024 19:123
  6. Post-transplant lymphoproliferative disorders (PTLD) are rare but severe complications that occur after solid organ or allogeneic hematopoietic stem cell transplantations (allo-HSCT), with rapid progression an...

    Authors: You-yuan Su, Ya-fei Yu, Zhen-yu Yan, Ya-jing Zhao, Jian-wei Lou, Feng Xue, Miao Xu, Qi Feng, Xue-bin Ji, Xiao-yuan Dong, Wen Wang, Chuan-fang Liu, Jun Peng and Xin-guang Liu
    Citation: Diagnostic Pathology 2024 19:122
  7. We explored Trichorhinophalangeal syndrome type 1 (TRPS1) expression in special types of breast carcinoma, and analyzed the correlation between TRPS1 and androgen receptor (AR) expression in triple-negative br...

    Authors: Change Kong, Baohua Yu, Rui Bi, Xiaoli Xu, Yufan Cheng, Wentao Yang and Ruohong Shui
    Citation: Diagnostic Pathology 2024 19:121
  8. Clear cell renal cell carcinoma (ccRCC) remains one of the most lethal urological malignancies even though a great number of improvements in diagnosis and management have achieved over the past few decades. Ac...

    Authors: Luojia Yang, Qin Wei, Xinran Chen, Yang Yang, Qingbo Huang, Baojun Wang and Xin Ma
    Citation: Diagnostic Pathology 2024 19:120
  9. Stathmin, a cytosolic microtubule-destabilizing phosphoprotein involved in the regulation of mitosis, is widely expressed in various malignancies and acts as an adverse prognostic factor. Our research analyzed...

    Authors: Adam Šafanda, Michaela Kendall Bártů, Romana Michálková, Marián Švajdler, Tetiana Shatokhina, Jan Laco, Radoslav Matěj, Gábor Méhes, Jana Drozenová, Jitka Hausnerová, Zuzana Špůrková, Jozef Škarda, Mária Hácová, Monika Náležinská, Pavel Dundr and Kristýna Němejcová
    Citation: Diagnostic Pathology 2024 19:118
  10. Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) is a cancer stem cell (CSC) marker of colorectal cancer and may be a CSC marker of other cancer types. Few studies have been conducted on LGR5...

    Authors: Hisashi Tamada, Takeshi Uehara, Takahiro Yoshizawa, Mai Iwaya, Shiho Asaka, Tomoyuki Nakajima, Masato Kamakura and Hiroyoshi Ota
    Citation: Diagnostic Pathology 2024 19:116
  11. Podoplanin (PDPN) is a transmembrane glycoprotein implicated in the pathogenesis of odontogenic lesions (OL). It is localized at the membrane and cytoplasmic level, and its interaction with other proteins coul...

    Authors: Mario Alberto Alarcón-Sánchez, Getsemani Luna-Bonilla, Selenne Romero-Servin and Artak Heboyan
    Citation: Diagnostic Pathology 2024 19:115
  12. Warthin tumor (WT) is the second most common benign tumor in salivary gland. It has a slow growth rate and most frequently occurs in the parotid gland. Most patients present with an incidental finding of a pai...

    Authors: Hai-Chao Tong, Shuang Ma, Lan Chen, Xiangyun Meng, Ying-Chun Li, Le-Yao Li, Lingyun Dong, Wan-Lin Zhang, Tyler Wildes, Lian-He Yang and Endi Wang
    Citation: Diagnostic Pathology 2024 19:114
  13. CLDN is a core component of tight junctions (TJs). Abnormal expressions of CLDNs are commonly detected in various types of tumors. CLDNs are of interest as a potential therapeutic target. CLDNs are closely ass...

    Authors: Xiaojie Fan, Aifeng Qi, Meng Zhang, Ying Jia, Shi Li, Dandan Han and Yueping Liu
    Citation: Diagnostic Pathology 2024 19:113
  14. The occurrence and progression of skin cutaneous melanoma (SKCM) is strongly associated with immune cells infiltrating the tumor microenvironment (TME). This study examined the expression, prognosis, and immun...

    Authors: Peipei Yang, Yunhui Jiang, Rong Chen, Junhan Yang, Mengting Liu, Xieping Huang, Ganglin Xu and Rui Hao
    Citation: Diagnostic Pathology 2024 19:112
  15. Lennert lymphoma (LL) is a variant of peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS), also known as a lymphoepithelioid variant of PTCL. Because of the rarity and lack of clear-cut diagnostic ...

    Authors: Shun Ding, Jiao Chen, Jiajun Su, Jiewen Liu, Weihua Yin and Fengjie Qi
    Citation: Diagnostic Pathology 2024 19:111
  16. Compared to primary breast sarcoma (BSs), radiotherapy-induced sarcoma (RIS) is a less frequent type of secondary breast sarcoma. Undifferentiated pleomorphic sarcoma (UPS) is an even rarer occurrence within t...

    Authors: Ting Lei, Zhiyi Shen, Mengjia Shen, Lingfang Du, Yongqiang Shi, Yan Peng, Zidi Zhou, Wenyue Da, Xi Chen and Qing Li
    Citation: Diagnostic Pathology 2024 19:110
  17. Clear cell odontogenic carcinoma (CCOC) is an odontogenic carcinoma characterized by sheets and islands of vacuolated and clear cells. The diagnosis of atypical CCOC can pose a challenge when tumor cells devia...

    Authors: Yanan Sun, Bo Li, Yaying Hu, Fu Chen, Junchen Pan, Yi Zhou and Jiali Zhang
    Citation: Diagnostic Pathology 2024 19:109
  18. Spindle epithelial tumor with thymus-like elements (SETTLE) is a rare malignant neoplasm of the thyroid gland which is believed to arise from intrathyroidal thymic tissue. It predominantly affects young adults...

    Authors: Prerna Chadha, Meenakshi Kamboj, Sunil Pasricha, Vikas Arora, Vishal Yadav, Manoj Gupta and Anurag Mehta
    Citation: Diagnostic Pathology 2024 19:108
  19. Surgical excision with clear histopathological margins is the preferred treatment to prevent progression of lentigo maligna (LM) to invasive melanoma. However, the assessment of resection margins on sun-damage...

    Authors: Jan Siarov, Darshan Kumar, John Paoli, Johan Mölne, Martin Gillstedt and Noora Neittaanmäki
    Citation: Diagnostic Pathology 2024 19:106

    The Correction to this article has been published in Diagnostic Pathology 2024 19:119

  20. Hepatocellular carcinoma (HCC) is a malignant tumor. It is estimated that approximately 50–80% of HCC cases worldwide are caused by hepatitis b virus (HBV) infection, and other pathogenic factors have been sho...

    Authors: Anyin Yang, Jianping Liu, Mengru Li, Hong Zhang, Xulei Zhang and Lianping Wu
    Citation: Diagnostic Pathology 2024 19:105

    The Correction to this article has been published in Diagnostic Pathology 2024 19:117

  21. Extraneural metastasis of central nervous system tumors is generally rare and most often reported in glioblastomas and medulloblastomas, whereas oligodendrogliomas seem to have the lowest risk of extracranial ...

    Authors: Nour Kurdi, Attila Mokánszki, Ingrid Balogh, Anikó Ujfalusi, Sándor Szabó, Gábor Méhes and Judit Bedekovics
    Citation: Diagnostic Pathology 2024 19:103
  22. Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) are a group of diseases with marked heterogeneity, including clinical, immunohistochemical, and molecular heterogeneity. T...

    Authors: Xiang Huang, Jiafei Zeng, Yuqing Luo, Shuai Luo, Yao Li and Jinjing Wang
    Citation: Diagnostic Pathology 2024 19:102
  23. There is currently scarcity of information on small cell neuroendocrine carcinoma of the nasopharynx (SCNEC-nasopharynx). It is believed that this type of cancer is not associated with Epstein-Barr virus (EBV)...

    Authors: Ying Chen, Ning Zhou, Caijun Huang, Xin He, Xiaodong Wang, Hao Tang, Wenyan Wang, Jiashuang Wang, Tao Li and Deyu Guo
    Citation: Diagnostic Pathology 2024 19:101
  24. Acinic cell carcinoma (AciCC) of the breast is a rare subtype of breast cancer. It was considered a low-grade triple-negative breast cancer (TNBC) with the potential to progress or transform into a high-grade ...

    Authors: Yunjie Ge, Xianping Wei, Jing-Nan Liu, Ping-Li Sun and Hongwen Gao
    Citation: Diagnostic Pathology 2024 19:100
  25. Bone marrow fibrosis (BMF) severely impacts both the quality of life and the efficacy of diagnostic procedures. However, the correlation between BMF and clinicopathological features, cytogenetic changes, and p...

    Authors: Xiumei Hu, Xiangyang Dai, Xinmeng Guo, Xingran Jiang, Yunlong Li, Hongying Zhao, Jun Lu, Xue Li and Mulan Jin
    Citation: Diagnostic Pathology 2024 19:99
  26. Rhabdomyosarcomas are aggressive tumors that comprise a group of morphologically similar but biologically diverse lesions. Owing to its rarity, Mixed pattern RMS (ARMS and ERMS) constitutes a diagnostic and th...

    Authors: Nehal K.H. Kamel and Eiman Adel Hasby
    Citation: Diagnostic Pathology 2024 19:98
  27. Immunohistochemistry (IHC) is widely used in the management of patients with cervical intraepithelial neoplasia (CIN) but still has many limitations in clinical practice. We analyzed the correlation of new bio...

    Authors: Shikang Qiu, Qiannan Wang, Huihui Jiang and Limin Feng
    Citation: Diagnostic Pathology 2024 19:97
  28. Mycobacterium avium complex (MAC) is an uncommon clinical pathogen, especially in the central nervous system (CNS), and carries a poor prognosis. MAC infections commonly present as immune reconstitution diseas...

    Authors: Mengyan Wang, Yahui Cui, Jinchuan Shi and Jun Yan
    Citation: Diagnostic Pathology 2024 19:96
  29. Uterine sarcoma is a rare and heterogeneous gynecological malignancy characterized by aggressive progression and poor prognosis. The current study aimed to investigate the relationship between clinicopathologi...

    Authors: Jin-feng Wang, Chen Li, Jing-yi Yang, Yue-ling Wang and Jing Ji
    Citation: Diagnostic Pathology 2024 19:94
  30. Cutaneous metastasis (CM) accounts for 5–30% of patients with breast cancer (BC) and presents unfavorable response to treatment and poor prognosis. A better understanding of the molecular alterations involved ...

    Authors: Yan Xu, Li Ding, Chao Li, Bin Hua, Sha Wang, Junli Zhang, Cuicui Liu, Rongyun Guo and YongQiang Zhang
    Citation: Diagnostic Pathology 2024 19:93
  31. Chordoma, a rare malignant tumor arising from notochordal tissue, usually occurs along the spinal axis. Only a few published reports of primary lung chordomas exist. Herein, we present a case of primary lung c...

    Authors: Naoko Shigeta, Tetsuya Isaka, Kyoko Ono, Mio Tanaka, Tomoyuki Yokose, Hiroyuki Adachi, Wataru Usuba and Hiroyuki Ito
    Citation: Diagnostic Pathology 2024 19:91
  32. Cerebral echinococcosis is relatively rare, and it is important to distinguish cerebral cystic echinococcosis (CCE) from cerebral alveolar echinococcosis (CAE) in terms of pathological diagnosis. We aim to des...

    Authors: Wenmei Ma, Zhiping Ma, Yi Shi, Xuelian Pang, Maiweilidan Yimingjiang, Zhe Dang, Wenli Cui, Renyong Lin and Wei Zhang
    Citation: Diagnostic Pathology 2024 19:90
  33. Waldenström’s macroglobulinemia (WM) is defined as a lymphoplasmacytic lymphoma (LPL) involving the bone marrow (BM) with presence of IgM monoclonal protein, and comprises > 95% of all LPL cases. Rituximab-bas...

    Authors: Shojiro Ichimata, Yukiko Hata, Kazuhiro Nomoto, Tsutomu Sato and Naoki Nishida
    Citation: Diagnostic Pathology 2024 19:89
  34. HER2-targeted therapies have recently emerged as an option in the management of metastatic colorectal cancer (mCRC) overexpressing HER2. However, data regarding HER2 status in primary CRC and its corresponding...

    Authors: Flavia D’Angelo, Franck Monnien, Alexis Overs, Irvin Pem, Fanny Dor, Marine Abad, Sophie Felix, Zohair Selmani, Zaher Lakkis, Christophe Borg, Alexandre Doussot, Fréderic Bibeau and Chloé Molimard
    Citation: Diagnostic Pathology 2024 19:88
  35. Pulmonary hamartomas are benign lung lesions. Histopathologically, pulmonary hamartoma is composed of varying amounts of mesenchymal elements, including chondroid tissue, mature adipose tissue, fibrous stroma,...

    Authors: Xiaoming Fan, Barry Breaux, Laura Leonards and Rusella Mirza
    Citation: Diagnostic Pathology 2024 19:87
  36. Follicular lymphoma (FL) is characterized by t(14;18)(q32;q21) involving the IGH and BCL2 genes. However, 10–15% of FLs lack the BCL2 rearrangement. These BCL2-rearrangement−negative FLs are clinically, pathologi...

    Authors: Sojung Lim, Jiwon Koh, Jeong Mo Bae, Hongseok Yun, Cheol Lee, Jin Ho Paik, Tae Min Kim and Yoon Kyung Jeon
    Citation: Diagnostic Pathology 2024 19:86
  37. Human pulmonary dirofilariasis (HPD) is rare in Hungary, and it stems from Dirofilaria immitis, mainly transmitted through mosquito bites, with dogs as primary hosts. Despite its prevalence in veterinary settings...

    Authors: Levente Kuthi, Tamás Zombori, László Tiszlavicz, Fanni Hegedűs, Szintia Almási, Bence Baráth, Mohammed Almakrami, Mohammad Jamal EJ, Nikolett Barta, Zsuzsanna Ujfaludi, Tibor Pankotai, Adrienn Hajdu, József Furák and Anita Sejben
    Citation: Diagnostic Pathology 2024 19:85
  38. Psoriasis is a disease of overactive immune system. OVOL1 and Filaggrin have been associated with many inflammatory skin lesions. To the best of our knowledge, the correlation between OVOL1 and Filaggrin in ps...

    Authors: Aiat Shaban Hemida, Mostafa Ahmed Hammam, Aya Ahmed Swilam and Wafaa Ahmed Shehata
    Citation: Diagnostic Pathology 2024 19:84
  39. Catenin (Cadherin-Associated Protein), Beta 1 (CTNNB1) genomic alterations are rare in prostate cancer (PCa). Gain-of-function mutations lead to overexpression of β-catenin, with consequent hyperactivation of the...

    Authors: Dilara Akhoundova, Stefanie Fischer, Joanna Triscott, Marika Lehner, Phillip Thienger, Sina Maletti, Muriel Jacquet, Dinda S.H. Lubis, Lukas Bubendorf, Wolfram Jochum and Mark A. Rubin
    Citation: Diagnostic Pathology 2024 19:83
  40. Ovarian clear cell carcinoma (OCCC), well known for its chemoresistance to platinum-based chemotherapy, exhibited a good response in clinical trials of anti–PD-1/PD-L1 inhibitors. By assessing PD-L1 expression...

    Authors: Yike Gao, Boju Pan, Hongbao Jia, Yang Zhang, Shu Wang, Yuming Wang, Sumei Zhang, Mei Li, Anqi Wang, Xiaoxi Wang, Kun Zhao, Zixin Zhang, Jian Sun, Dan Guo and Zhiyong Liang
    Citation: Diagnostic Pathology 2024 19:82
  41. Neuroendocrine carcinoma arising from the urachus is extremely rare. We describe a case of a 33-year-old gentleman who presented with hematuria and diagnosed to have a composite adenocarcinoma and small cell n...

    Authors: Sarah Obiedat, Khaled Murshed, Lajos Szabados, Khaled Al Rumaihi and Issam Al Bozom
    Citation: Diagnostic Pathology 2024 19:81
  42. Intravascular papillary endothelial hyperplasia (IPEH) represents an uncommon reactive endothelial hyperplastic proliferation. A 46-year-old man experienced increased volume in the right maxilla, elevation of...

    Authors: Mateus José Dutra, Ana Lia Anbinder, Christyan Moretti Pereira, Beatriz Afonso Chiliti, André Caroli Rocha and Estela Kaminagakura
    Citation: Diagnostic Pathology 2024 19:80
  43. Osteosarcoma is a bone tumor that is characterized by high malignancy and a high mortality rate, and that originates from primitive osteoblastic mesenchymal cells and is most common in rapidly growing long bon...

    Authors: Jiabin Lai, Weike Kong, Qiangchang Fu, Zhaochang Jiang, Bohao Sun, Xin Ye, Jing Kong, Shumei Wei and Lifeng Jiang
    Citation: Diagnostic Pathology 2024 19:79

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